Hi Thomas,
Yes JT65 works well. I had 120 JT65B 144MHz EME QSOs remotely from my station last year as GB2EME with no real problems.
Do not use any compression, A-Law etc as they do distort the incoming signal and that will fool the JT65 decoder on very weak signals.
I used 16 bit 8KHz for an easy life - you do not need to carefuly set levels. I have decoded callsigns on 144MHz JT65B EME at -29/-30 at times.
With very careful setting of all levels; rig, RRC-1258 and computer I have used linear 12bits bits 8KHz. With 8 bit A-law I have had some QSOs but would not use it for weak signal working.
73
John G4SWX